As part of an interview with RedOctane co-founders Kai and Charles Huang, the following was stated regarding the future of Guitar Hero for the Nintendo Wii.
The brothers say they’ll also stretch the game’s capabilities on the Nintendo Wii console. Although "Guitar Hero III" is already available on the Wii, the capabilities of the console’s unique motion-sensitive controller could allow RedOctane to dramatically alter the gaming experience. The Huangs are closely studying the Wii because the platform attracts players who want the added social benefit of playing with other people.”